武汉大学药学院王连荣研究组
City and Nature Symbiosis Green and World Peer

当前位置:

(1)       Xiaolin Xiong, Geng Wu, Yue Wei, Liqiong Liu, Yubing Zhang, Rui Su, Xianyue Jiang, Mengxue Li, Haiyan Gao, Xihao Tian, Yizhou Zhang, Li Hu, Si Chen, You Tang, Susu Jiang, Ruolin Huang, Zhiqiang Li, Yunfu Wang, Zixin Deng, Jiawei Wang, Peter C. Dedon, Shi Chen, Lianrong Wang*. SspABCD-SspE is a phosphorothioation-sensing bacterial defense system with broad antiphage activities, Nature Microbiology, 2020, July, 5: 917-928. DOI: 10.1038/s41564-020-0700-6.(影响因子:30.964

(2)      Dan Wu#, Yaqian Tang, Siwei Chen, Yue He, Xiaofei Chang, Wenzhong Zheng, Zixin Deng, Zhiqiang Li, Lianrong Wang*, Geng Wu & Shi Chen. The functional coupling between restriction and DNA phosphorothioate modification systems underlying the DndFGH restriction complex. Nature Catalysis. 2022, December, Volume 5, 1131–1144. (影响因子:40.706

(3)      Xiaolin Wu#, Bo Cao# , Patricia AquinoTsu-Pei ChiuChao ChenSusu Jiang , Zixin DengShi Chen , Remo RohsLianrong Wang*, James E Galagan*, Peter C Dedon*. Epigenetic Competition Reveals Density-Dependent Regulation and Target Site Plasticity of Phosphorothioate Epigenetics in Bacteria. Proc Natl Acad Sci U S A. 2020, June, 117 (25):14322-14330. DOI: 10.1073/pnas.2002933117.(影响因子:12.779

(4)      Xuan Zou#, Xiaohong Xiao, Ziran Mo, Yashi Ge, Xing Jiang, Ruolin Huang, Mengxue Li, Zixin Deng, Shi Chen*, Lianrong Wang*, Sang Yup Lee*. Systematic strategies for developing phage resistant Escherichia coli strains. Nature Communications, 2022, 13: 4491. (影响因子: 17.694

(5)       Haiyan Gao, Xinqi Gong, Jinchuan Zhou , Yubing Zhang, Jinsong Duan, Yue Wei, Liuqing Chen, Zixin Deng, Jiawei Wang, Shi Chen*, Geng Wu *, Lianrong Wang*. Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nature Communications, 2022, November, 13:6773. (影响因子: 17.694

(6)      Ming-Yu Wu#, Luojia Chen, Qingrong Chen, Rui Hu, Xiaoyu Xu, Yifei Wang, Jie Li, Shun Feng, Changjiang Dong, Xiao-Lian Zhang, Zhiqiang Li, Lianrong Wang,* Shi Chen,* and Meijia Gu*. Engineered Phage with Aggregation-Induced Emission Photosensitizer in Cocktail Therapy against Sepsis. Advanced Materials. 2023, 35, 2208578, DOI: 10.1002/adma.202208578. (影响因子: 32.086

(7)      Yue Wei#, Qinqin Huang, Xihao Tian, Mingmin Zhang, Junkai He, Xingxiang Chen, Chao Chen, Zixin Deng, Zhiqiang Li, Shi Chen, and Lianrong Wang*, Single-molecule optical mapping of the distribution of DNA phosphorothioate epigenetics. Nucleic Acids Research, 2021, Doi: 10.1093/nar/gkab169.(影响因子: 19.160

(8)      Ming-Yu Wu, Meijia Gu, Jong-Kai Leung, Xinmei Li, Yuncong Yuan, Chao Shen, Lianrong Wang*, Engui Zhao*, Sijie Chen*. A Membrane-Targeting Photosensitizer with Aggregation-Induced Emission Characteristics for Highly Efficient Photodynamic Combat of Human Coronaviruses. Small, 2021, June, https://doi.org/10.1002/smll.202101770.(影响因子: 15.153

(9)       Bo Cao#, Chao Chen#, Michael S. DeMott#, Qiuxiang Cheng, Tyson A. Clark, Xiaolin Xiong, Xiaoqing Zheng, Vincent Butty, Stuart S. Levine, George Yuan, Matthew Boitano, Khai Luong, Yi Song, Xiufen Zhou, Zixin Deng, Stephen W. Turner, Jonas Korlach, Delin You*, Lianrong Wang*, Shi Chen*, Peter C. Dedon. Genomic mapping of phosphorothioates reveals partial modification of short consensus sequences. Nature Communications. 2014, 5: 3951. (影响因子: 17.694

(10)    Wenzhong Zheng#, Kexin Wang#, Yachen Wu#, Ge Yan, Chi Zhang, Zhiqiang Li, Lianrong Wang*, Shi Chen*. C9orf72 regulates the unfolded protein response and stress granule formation by interacting with eIF2α. Theranostics. : 2022, Oct, 17, , Vol. 12, Issue 17. (影响因子: 11.600

(11)    You Tang#, Yue Hong,  Li Liu,  Xuan Du,  Yaqi Ren,  Susu Jiang, Wanjing Liu,  Chen Chao, Zixin Deng, Lianrong Wang*, Shi Chen*. Involvement of the DNA Phosphorothioation System in TorR Binding and Anaerobic TMAO Respiration in Salmonella enterica. mBio, 2022,  April 14, Vol. 13, No. 3. (影响因子: 7.786

(12)    He W#, Gao H#, Wu D, Jiang S, Huang W, Chen C, Deng Z, Xiong L, Wu G*, Wang L*. Structural and Functional Analysis of DndE Involved in DNA Phosphorothioation in the Haloalkaliphilic Archaea Natronorubrum bangense JCM10635. mBio. 2022 Apr 14:e0071622. doi: 10.1128/mbio.00716-22. (影响因子: 7.786

(13)   Pengqing Nie#, Zhiqiang Li#, Yimeng Wang, Yubing Zhang, Mengna Zhao, Jie Luo, Shiming Du, Zixin Deng, Jincao Chen, Yunfu Wang, Shi Chen, Lianrong Wang*. Gut microbiome interventions in human health and diseases. Medicinal Research Reviews, 2019 Apr 17. doi: 10.1002/med.21584. (影响因子: 12.388)

(14)   Lianrong Wang, Susu Jiang, Chao Chen, Wei He, Xiaolin Wu, Fei Wang, Tong Tong, Xuan Zou, Zhiqiang Li, Jie Luo, Zixin Deng, and Shi Chen*. Synthetic Genomics: From DNA Synthesis to Genome Design, Angew Chemie Int Ed, 2018, Feb, 57(7): 1748–1756. (影响因子: 16.823)

(15)   Lianrong Wang, Susu Jiang, Zixin Deng, Peter Dedon, Shi Chen*.  DNA phosphorothioate modification – a new multifunctional epigenetic system in bacteria. FEMS Microbiology Reviews. 2019, 43(2): 109~122 doi.org/10.1093/femsre/fuy036. (影响因子: 15.177)

(16)    Lianrong Wang#, Shi Chen#, Tiegang Xu, Koli Taghizadeh, John S Wishnok, Xiufen Zhou, Delin You, Zixin Deng*, Peter C Dedon*. Phosphorothioation of DNA in bacteria by dnd genes. Nature Chemical Biology. 2007;3(11):709-10. (影响因子: 16.174)

(17)   Lianrong Wang, Shi Chen*, Kevin L. Vergin, Stephen J. Giovannoni, Simon W. Chan, Michael S. DeMott, Koli Taghizadehe, Otto X. Cordero, Michael Cutler, Sonia Timberlake, Eric J. Alm, Martin F. Polz, Jarone Pinhassi, Zixin Deng, Peter C. Dedon*. DNA phosphorothioation is widespread and quantized in bacterial genomes. Proc Natl Acad Sci USA. 2011; 108(7):2963-8. (影响因子:12.779)

(18)   Fei Wang#, Lianrong Wang#, Xuan Zou, Suling Duan, Zhiqiang Li, Zixin Deng, Jie Luo, Sang Yup Lee*, Shi Chen*. Advances in CRISPR-Cas systems for RNA targeting, tracking and editing. Biotechnology Advances. 2019, Mar 27. pii: S0734-9750(19)30052-7. doi: 10.1016/j.biotechadv.2019.03.016. (影响因子:17.681)

(19)   Chao Chen#, Lianrong Wang#, Si Chen, Xiaolin Wu, Meijia Gu, Xi Chen, Susu Jiang, Yunfu Wang Zixin Deng, Peter C. Dedon, Shi Chen*. Convergence of DNA methylation and phosphorothioation epigenetics in bacterial genomes. Proc Natl Acad Sci U S A, 2017, Apr, doi: 10.1073/pnas.1702450114. (影响因子: 12.779)

(20)   Xuan Zou#, Lianrong Wang#, Zhiqiang Li, Jie Luo, Yunfu Wang, Zixin Deng, Shiming Du, Shi Chen*. Genome engineering and modification toward synthetic biology for the production of antibiotics. Medicinal Research Reviews, 2018, Jan, 38(1): 229~260. (影响因子: 12.388)

(21)   Tong Tong#, Si Chen#, Lianrong Wang#, You Tang#, Jae Yong Ryu, Susu Jiang, Xiaolin Wu, Chao Chen, Jie Luo, Zixin Deng, Zhiqiang Li, Sang Yup Lee*, Shi Chen*. Occurrence, evolution, and functions of DNA phosphorothioate epigenetics in bacteria, Proc Natl Acad Sci U S A, 2018, 2018,115(13):2988-2996. doi:10.1073/pnas.1721916115. (影响因子:12.779)

(22)   Shiwei Wang, Mengping Wan, Ruolin Huang,a Yujing Zhang, Yuqing Xie, YueWei, Mustafa Ahmad, Dan Wu, Yue Hong, Zixin Deng, Shi Chen, Zhiqiang Li, Lianrong Wang*. SspABCD-SspFGH Constitutes a New Type of DNA Phosphorothioate-Based Bacterial Defense System. mBio, 2021, 12(2) e00613-21, DOI:10.1128/mBio. 00613-21. (影响因子: 7.786)

(23)   Cheng Zhang, Pengqing Nie, Chunliu Zhou, Yue Hu, Suling Duan, Meijia Gu, Dongxu Jiang, YunfuWang. Zixin Deng, Jincao Chen, Shi Chen and Lianrong Wang*. Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner. Cell Death and Disease, 2021 12:209. Doi.org/10.1038/s41419-021-03484-3. (影响因子: 9.685)

(24)   Liqiong Liu#, Susu Jiang#, Mai Xing, Chao Chen, Chongde Lai, Na Li, Guangfeng Liu, Dan Wu, Haiyan Gao, Liang Hong, Pan Wu, Shi Chen, Zixin Deng, Geng Wu,* Lianrong Wang*. Structure of a L-cysteine desulfurase from a Ssp DNA phosphorothioation system in Vibrio cyclitrophicus. mBio, 2020, 11(2), DOI:10.1128/mBio.00488-20. (影响因子: 7.786)

(25)   Yuanjiao Li, Jingjing Liu, Yajie Wang, Ho Wai Chan, Lianrong Wang*, Wan Chan*. Mass Spectrometric and Spectrophotometric Analyses Reveal an Alternative Structure and a New Formation Mechanism for Melanin. Analytical Chemistry, 2015, 87, 7958−7963. (影响因子:8.008)

(26)   Shuangju Wu#, Lianrong Wang#, Rui Gan, Tong Tong, Hao Bian, Zhiqiang Li, Shiming Du, Zixin Deng, Shi Chen*. Signature arsenic detoxification pathways in Halomonas sp. GFAJ-1, mBio, 2018 May 1; 9 (3): e00515-18. doi: 10.1128/mBio.00515-18. (影响因子: 7.786)